We received the following notification pursuant to § 21 para. 1 of the WpHG on 26 April 2007:

The following notification is made in the names of Threadneedle Asset Management Limited, Threadneedle Asset Management Holdings Limited, both with registered seat at London, United Kingdom and in the name of Ameriprise Financial, Inc., Minneapolis, USA.

Ameriprise Financial Inc. is the parent company of Threadneedle Asset Management Holdings Limited, which is the parent company of Threadneedle Asset Management Limited.

The share of voting stocks of the above mentioned companies in RHÖN-KLINIKUM AG, Salzburger Leite 1, 97616 Bad Neustadt a.d.Saale, Germany went above the threshold of 5 % of the total voting stocks of the company on 12 April 2007.

The percentage of voting rights of Threadneedle Asset Management Limited in RHÖN-KLINIKUM AG at 12 April 2007 amounted to 5,01 % (2,598,050 shares). These voting rights are in their entirety attributable to Threadneedle Asset Management Limited pursuant to § 22 para. 1 sent. 1 No. 6 WpHG.

The percentage of voting rights of Threadneedle Asset Management Holdings Limited in RHÖN-KLINIKUM AG at 12 April 2007 amounted to 5,01 % (2,598,050 shares). These voting rights are in their entirety attributable to Threadneedle Asset Management Holdings Limited pursuant to § 22 para. 1 sent. 1 No. 6, sent. 2 and sent. 3 WpHG.

The percentage of voting rights of Ameriprise Financial, Inc. in RHÖN-KLINIKUM AG at 12 April 2007 amounted to 5,01 % (2,598,050 shares). These voting rights are in their entirety attributable to Ameriprise Financial, Inc. pursuant to § 22 para. 1 sent. 1 No. 6, sent. 2 and sent. 3 WpHG.

Bad Neustadt a.d.Saale, May 2007

The Board of Management